Director Shareholding

GlaxoSmithKline PLC
5 February 2002

                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


1 February 2002     The Administrators of the GlaxoSmithKline US Retirement 
                    Savings Plan ('the Plan') notified GlaxoSmithKline plc on 
                    the 4 February 2002, that as a result of movement in the 
                    fund on the 1 February 2002, the number of Ordinary Share 
                    ADRs held by the fund had increased from 18,565,290 to 
                    18,648,299 at an average price of $47.5000.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.




S M Bicknell

Company Secretary


5 February 2002



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