Director Shareholding

GlaxoSmithKline PLC
2 January 2002

                             Directors' Interests



I give below details of a change in the interests in Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the undermentioned Director arising from the purchase of Ordinary Share ADRs
on 20 December 2001 through the quarterly investment element of the US Global
BuyDirect Plan administered by The Bank of New York, which Mr McArthur entered
on 4 May 1997:-


Mr J H         Beneficial interest in 142.6683 Ordinary Share ADRs purchased at
McArthur       a price of US$ 49.17 per ADR.


Mr McArthur and the Company were advised of this information on 24 December
2001.


S M Bicknell

Company Secretary

2 January 2002