Director Shareholding

GlaxoSmithKline PLC 14 December 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 13 The Administrators of the GlaxoSmithKline Retirement Savings Plan December ('the Plan') notified GlaxoSmithKline plc on the 14 December 2001, 2001 that as a result of movement in the fund on the 13 December 2001, the number of Ordinary Share ADRs held by the fund had decreased from 18,756,344 to 18,734,443 at an average price of $50.1900 The Plan is a discretionary fund of which all employees or former employees of SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier is therefore, interested in the shares held in the fund from time to time in the same way as other employees or former employees of SmithKline Beecham plc and its subsidiaries. S M Bicknell Company Secretary 14 December 2001

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