Director Shareholding

GlaxoSmithKline PLC
7 January 2002

                             Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

4       The Administrators of the SmithKline Beecham Employee Benefit Trust
January ('the Trust') notified the Company on the 7 January 2002, that 22,956
2002    Ordinary shares had been transferred from the Trust to participants of
        the SmithKline Beecham 1991 Share Option Plan.

The Trust is a discretionary fund of which all employees or former employees
of SmithKline Beecham plc and its subsidiaries are potential beneficiaries.
One of the Company's directors, Dr J P Garnier is therefore, interested in the
shares held in the fund from time to time in the same way as other employees
or former employees of SmithKline Beecham plc and its subsidiaries.


S M Bicknell

Company Secretary


7 January 2002