Director Shareholding

GlaxoSmithKline PLC
11 March 2002





                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

8 March 2002    Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome 
                Employee Trust ("the Trust"), transferred 21,270 Ordinary Shares 
                in the Company to participants of the Glaxo Wellcome 1999 Share 
                Option Plan and the Glaxo Wellcome International Share Option 
                Scheme.




The Company was advised of this transaction on 11 March 2002.




The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries
are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes
and John Coombe are therefore interested in the shares held in the Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline Services plc and its subsidiaries.






S M Bicknell

Company Secretary




11 March 2002




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