Director Shareholding

GlaxoSmithKline PLC
12 March 2002



                              Directors' Interests


I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £17.23 per Ordinary Share on 11 March
2002 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:


Mr J D Coombe       Acquisition of 7 Ordinary Shares under the partnership 
                    element of the Plan (personal contribution)

                    Acquisition of 7 Ordinary Shares under the matching element 
                    of the Plan (Company contribution)


Mr Coombe and the Company were advised of this information on 12 March 2002


S M Bicknell

Company Secretary


12 March 2002


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