Director Shareholding

GlaxoSmithKline PLC
30 April 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

29 April 2002                 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust
                              ("the Trust"), transferred 14,284 Ordinary Shares in the Company to participants
                              of the Glaxo Wellcome 1999 Share Option Plan, the Glaxo Wellcome International
                              Share Option Scheme and the Glaxo Wellcome 1999 Long Term Incentive Plan. The
                              Trust also sold 2,671 Ordinary Shares in the Company at £16.82 per share.




The Company was advised of these transactions on 30 April 2002.




The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.






S M Bicknell

Company Secretary




30 April 2002




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