Director Shareholding

GlaxoSmithKline PLC
2 April 2002


                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

27 March 2002      Abacus (GW) Trustees Limited, as trustee of The Glaxo 
                   Wellcome Employee Trust ("the Trust"), transferred 60,278 
                   Ordinary Shares in the Company to participants of the Glaxo 
                   Wellcome 1999 Share Option Plan, the Glaxo Wellcome UK Share 
                   Option Scheme and the Glaxo Wellcome International Share 
                   Option Scheme. The Trust also sold 10,903 Ordinary Shares in 
                   the Company at £16.22 per share.


The Company was advised of these transactions on 28 March 2002.


The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services plc and its subsidiaries.


S M Bicknell
Company Secretary

2 April 2002


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