Director Shareholding

GlaxoSmithKline PLC
24 May 2002

                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

23 May 2002    The Administrators of the GlaxoSmithKline US Retirement Savings 
               Plan ("the Plan") notified GlaxoSmithKline plc on the 24 May 
               2002, that as a result of movement in the fund on the 23 May 
               2002, the number of Ordinary Share ADRs held by the fund had 
               decreased from 18,387,504 to 18,351,699 at an average price of 
               $46.3900.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.



S M Bicknell

Company Secretary

24 May 2002



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