Director Shareholding

GlaxoSmithKline PLC
27 May 2002

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

24 May 2002                  The Administrators of the SmithKline Beecham 
                             Employee Benefit Trust ("the Trust") notified the 
                             Company on the 27 May 2002 that 74,455 Ordinary 
                             shares had been transferred from the Trust to 
                             participants of the SmithKline Beecham 1991 Share
                             Option Plan.

The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell
Company Secretary

27 May 2002


                      This information is provided by RNS
            The company news service from the London Stock Exchange