Director Shareholding

GlaxoSmithKline PLC
29 July 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

25 July 2002                      The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 26 July 2002, that as a result of
                                  movement in the fund on the 25 July 2002, the number of Ordinary Share ADRs held
                                  by the fund had decreased from 18,093,787 to 18,008,351 at an average price of
                                  $35.61.




The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.








S M Bicknell

Company Secretary


29 July 2002




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