Director Shareholding

GlaxoSmithKline PLC
22 July 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

18 July 2002                      The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 19 July 2002, that as a result of
                                  movement in the fund on the 18 July 2002, the number of Ordinary Share ADRs held
                                  by the fund had decreased from 18,132,793 to 18,029,764 at an average price of
                                  $36.92.



The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell

Company Secretary

22 July 2002




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