Director Shareholding

GlaxoSmithKline PLC
16 April 2002



                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

15 April 2002                 Abacus (GW) Trustees Limited, as trustee of The 
                              Glaxo Wellcome Employee Trust ("the Trust"), 
                              transferred 4,978 Ordinary Shares in the Company 
                              to a participant of the Glaxo Wellcome 1999 Long 
                              Term Incentive Plan

The Company was advised of these transactions on 16 April 2002.

The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.

S M Bicknell

Company Secretary

16 April 2002




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