Director Shareholding

GlaxoSmithKline PLC
25 April 2002


                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

24 April 2002      Abacus (GW) Trustees Limited, as trustee of The Glaxo      
                   Wellcome Employee Trust (the Trust"), transferred 4,167 
                   Ordinary Shares in the Company to participants of the Glaxo 
                   Wellcome 1999 Share Option Plan and the Glaxo Wellcome 1999 
                   Long Term Incentive Plan. The Trust also sold 1,064 Ordinary 
                   Shares in the Company at £16.4577 per share.


The Company was advised of these transactions on 25 April 2002.

The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.



S M Bicknell

Company Secretary

25 April 2002


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