Director Shareholding

GlaxoSmithKline PLC
05 November 2002



                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


30 October 2002                  The Administrators of the GlaxoSmithKline US Retirement Savings
                                 Plan ("the Plan") notified GlaxoSmithKline plc on 4 November
                                 2002, that as a result of movement in the fund on the 30 October
                                 2002, the number of Ordinary Share ADRs held by the fund had
                                 increased from 18,074,815 to 18,813,090 at an average price of
                                 $37.68.

The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.




S M Bicknell

Company Secretary


5 November 2002


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