Director Shareholding

GlaxoSmithKline PLC
11 October 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

3 October 2002                    The Administrators of the GlaxoSmithKline US 
                                  Retirement Savings Plan ("the Plan") notified 
                                  GlaxoSmithKline plc on the 11 October 2002, 
                                  that as a result of movement in the fund on 
                                  the 3 October 2002, the number of Ordinary 
                                  Share ADRs held by the fund had decreased from 
                                  18,177,489 to 17,993,362 at an average price
                                  of $40.21.

The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.

S M Bicknell

Company Secretary


11 October 2002


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