Director Shareholding

GlaxoSmithKline PLC
15 November 2002

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

14 November 2002       The Administrators of the GlaxoSmithKline US Retirement 
                       Savings Plan ("the Plan") notified GlaxoSmithKline plc on 
                       15 November 2002, that as a result of movement in the 
                       fund on the 14 November 2002, the number of Ordinary 
                       Share ADRs held by the fund had decreased from 18,181,432 
                       to 18,177,123 at an average price of $39.69.


The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.





S M Bicknell

Company Secretary

15 November 2002


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