Director Shareholding

GlaxoSmithKline PLC
30 September 2002





                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


27 September 2002          The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                           Trust") notified the Company on the 30 September 2002 that 73,415 Ordinary
                           shares had been transferred from the Trust to participants of the SmithKline
                           Beecham 1991 Share Option Plan.





The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.







S M Bicknell

Company Secretary

30 September 2002


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