Director Shareholding

GlaxoSmithKline PLC
23 December 2002

                              Directors' Interests

I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-

Dr J P Garnier                      The Administrators of the SmithKline Beecham 
                                    Senior Executive Bonus Investment Plan 
                                    notified the Company and Dr Garnier on 
                                    23 December 2002 that he had increased his 
                                    interest by 11.654 Ordinary Share ADRs
                                    at an average price of $47.45 per share 
                                    following the re-investment of the interest 
                                    accrued on his account which took place on 
                                    2 April 2002.


SM Bicknell

Company Secretary

23 December 2002




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