Director Shareholding

GlaxoSmithKline PLC
03 February 2003

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

31 January 2003          The Administrators of the GlaxoSmithKline US Retirement 
                         Savings Plan ("the Plan") notified GlaxoSmithKline plc 
                         on 3 February 2003, that as a result of movement in the 
                         fund on the 31 January 2003, the number of Ordinary 
                         Share ADRs held by the fund had increased from 
                         18,261,048 to 18,296,820 at an average price of $38.76.


The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell

Company Secretary

3 February 2003


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