Director Shareholding

GlaxoSmithKline PLC
27 January 2003





                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

23 January 2003  The Administrators of the GlaxoSmithKline US Retirement Savings
                 Plan ("the Plan") notified GlaxoSmithKline plc on 24 January
                 2003, that as a result of movement in the fund on the 23 
                 January 2003, the number of Ordinary Share ADRs held by the 
                 fund had increased from 18,263,970 to 18,287,511 at an average 
                 price of 36.65.




The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.




S M Bicknell

Company Secretary


27 January 2003


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