Director Shareholding

GlaxoSmithKline PLC
19 March 2003





                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



14 March 2003              The Administrators of the SmithKline Beecham Employee
                           Benefit Trust ('the Trust') notified the Company on 18
                           March 2003 that 67,369 Ordinary shares had been transferred
                           from the Trust to participants of the SmithKline Beecham
                           1991 Share Option Plan.


                           The trust also sold 16,174 ordinary shares on 10 March 2003
                           at a price of £10.54 per share.


                           The trust also sold 1,278 ordinary shares on 11 March 2003
                           at a price of £10.33 per share.


                           The trust also sold 3,787 ordinary shares on 12 March 2003
                           at a price of £10.09 per share.


                           The trust also sold 838 ordinary shares on 14 March 2003 at
                           a price of £11.08 per share.


                           The trust also sold 101 ordinary shares on 14 March 2003 at
                           a price of £11.08 per share.


                           The Administrators of the SmithKline Beecham Employee
                           Benefit Trust, ('the Trust') notified the Company on 18
                           March 2003 that 6,232 Ordinary shares had been transferred
                           from the Trust to a participant in the UK Bonus Investment
                           Plan.




The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell

Company Secretary

19 March 2003


                      This information is provided by RNS
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