Director Shareholding

GlaxoSmithKline PLC
17 April 2003

                              Directors' Interests



I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £12.12 per Ordinary Share on 17 April
2003 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:



Mr J D Coombe                      Acquisition of 3 Ordinary Shares under the Dividend Reinvestment element
                                   of the Plan (Company contribution)



Mr Coombe and the Company were advised of this information on 17 April 2003.






S M Bicknell

Company Secretary


17 April 2003


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