Director Shareholding

GlaxoSmithKline PLC
02 May 2003

                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



28 April 2003              Abacus (GSK) Trustees Limited, as trustee of the
                           GlaxoSmithKline Employee Trust, ("the GSK Trust"),
                           transferred 41,220 Ordinary Shares in the Company to
                           participants in the SmithKline Beecham 1991 Plan.

29 April 2003              The GSK Trust transferred 51,346 Ordinary Shares in
                           the Company to participants in the SmithKline Beecham
                           1991 Plan.

30 April 2003              The GSK Trust transferred 1,611 Ordinary Shares in
                           the Company to participants in the SmithKline Beecham
                           1991 Plan.




The Company was advised of these transactions on 2 May 2003.


The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr J-P Garnier and Mr J D Coombe
are therefore interested in the shares held in the GSK Trust from time to time
in the same way as other employees or former employees of GlaxoSmithKline plc
and its subsidiaries.


S M Bicknell

Company Secretary


2 May 2003


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