Director Shareholding

GlaxoSmithKline PLC
11 June 2003


                              Directors' Interests

I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £12.5968 per Ordinary Share on 10 June
2003 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:


Mr J D Coombe        Acquisition of 10 Ordinary Shares under the partnership 
                     element of the Plan (personal contribution)

                     Acquisition of 10 Ordinary Shares under the matching 
                     element of the Plan (Company contribution)

Mr Coombe and the Company were advised of this information on 11 June 2003.


S M Bicknell
Company Secretary

11 June 2003


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