Director Shareholding

GlaxoSmithKline PLC
13 October 2003

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

8 October 2003               The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                             Trust") notified the Company on the 13 October 2003 that 1,253 Ordinary
                             shares had been purchased for participants in the SmithKline Beecham Bonus
                             Investment Plan at a price of £12.89 per share.


                             The Trust also notified the Company on 13 October 2003 that 1,663 Ordinary
                             shares had been purchased for participants in the GlaxoSmithKline Annual
                             Investment Plan at a price of £12.85 per share.


The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.



S M Bicknell
Company Secretary
13 October 2003



                      This information is provided by RNS
            The company news service from the London Stock Exchange