Director Shareholding

GlaxoSmithKline PLC
10 October 2003



                              Director's Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-


Mr J D Coombe                 The Administrators of the GlaxoSmithKline Annual Investment Plan
                              notified the Company and Mr Coombe on 9 October 2003 that he had
                              increased his interest by 102 Ordinary Shares at a price of £12.85 per
                              share following the re-investment of the dividend paid to shareholders
                              on 2 October 2003.







S M Bicknell
Company Secretary
10 October 2003




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