Director Shareholding

GlaxoSmithKline PLC
05 January 2004

                              Directors' Interests


I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.


On 31 December 2003, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the automatic share allocation arrangements for non-executive Directors
for the period of service from 1 October to 31 December 2003, as listed below.


Non Executive Director                Ordinary Shares         American Depository
                                                                 Shares (ADS)
Sir Christopher Hogg                       1,500
Dr Michele Barzach                          250
Mr Lawrence Culp                                                      125
Mr Crispin Davis                            250
Sir Peter Job                               250
John McArthur                                                         125
Donald McHenry                                                        125
Sir Ian Prosser                             250
Dr Ronaldo Schmitz                          250
Dr Lucy Shapiro                                                       125
Sir Robert Wilson                         166.6667




At the same time the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share election element of the share allocation arrangements for
non-executive Directors for the period of service from 1 October to 31 December
2003, as listed below.




Non Executive Director                Ordinary Shares        American Depositary
                                                                    Shares

                                                                     (ADS)

Sir Christopher Hogg                     2938.8715
Mr Lawrence Culp                                                   389.7510
Mr Crispin Davis                          881.6614
Sir Peter Job                             881.6614
Sir Ian Prosser                           538.7931
Dr Ronaldo Schmitz                        431.0345


The Company and the directors were informed of these allocations on 5 January
2004.


S M Bicknell

Company Secretary

5 January 2004


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