Director Shareholding

GlaxoSmithKline PLC
03 November 2003

                              Director's Interests

I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:


Dr J P Garnier       The Administrators of the GlaxoSmithKline US Retirement 
                     Savings Plan notified GlaxoSmithKline plc on 31 October 
                     2003 that Dr Garnier had increased his interest by 28 
                     Ordinary Share ADRs at a price of $43.36 per share on 30 
                     October 2003. Dr Garnier was also notified of this change 
                     on 31 October 2003.


S M Bicknell
Company Secretary
3 November 2003


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