Director Shareholding

GlaxoSmithKline PLC
19 January 2004

                              Director's Interests

The Administrators of the GlaxoSmithKline US Retirement Savings Plan notified
GlaxoSmithKline plc and the under-mentioned Directors on 19 January 2004 of an
increase in their interests in Ordinary Share ADRs on 16 January 2004 at a price
of $44.85 per share:-




Dr J P Garnier                                                           78
Dr T Yamada                                                              37



S M Bicknell

Company Secretary

19 January 2004


                      This information is provided by RNS
            The company news service from the London Stock Exchange