Director Shareholding

GlaxoSmithKline PLC
01 March 2004





                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



1 March 2004                 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                             Trust") notified the Company on 1 March 2004 that 17,520 Ordinary shares
                             had been transferred from the Trust to a participant in the SmithKline
                             Beecham Bonus Investment Plan.



The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, John Coombe is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.






S M Bicknell

Company Secretary


1 March 2004



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