Director Shareholding

GlaxoSmithKline PLC
01 March 2004


                              Directors' Interests

The Administrators of the GlaxoSmithKline US Retirement Savings Plan notified
GlaxoSmithKline plc and the under-mentioned Directors on 1 March 2004 of an
increase in their interests in Ordinary Share ADRs on 27 February 2004 at a
price of $42.62 per share:-




Dr J P Garnier                                                           63
Dr T Yamada                                                              55



S M Bicknell

Company Secretary

1 March 2004


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