Director Shareholding

GlaxoSmithKline PLC
30 June 2004


                              Directors' Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:

Sir Christopher Hogg acquired a beneficial interest in 47 Ordinary Shares
purchased under a Personal Equity Plan on 28 June 2004 at £11.50.

Mr J D Coombe acquired a beneficial interest in 14 Ordinary Shares purchased
under a Personal Equity Plan on 28 June 2004 at £11.50.

Mrs G A Coombe (wife of Mr J D Coombe) acquired a beneficial interest in 10
Ordinary Shares purchased under a Personal Equity Plan on 28 June 2004 at
£11.50.

Sir Peter Job acquired a beneficial interest in 2 Ordinary Shares purchased
under a Personal Equity Plan on 28 June 2004 at £11.50.

The Directors and the Company were advised of these transactions on 29 June
2004.


S M Bicknell
Company Secretary

30 June 2004


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