Director Shareholding

GlaxoSmithKline PLC
12 January 2004




                              Director's Interests


I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of the
under-mentioned Directors arising from the reinvestment of the dividend paid to
Ordinary Share ADR holders on 6 January 2004 through the US Global BuyDirect
Plan administered by The Bank of New York:


Mr D F McHenry                      Beneficial interest in 0.2594 of an Ordinary 
                                    Share ADR purchased at a
                                    price of $45.8689 per ADR.

Mr J H McArthur                     Beneficial interest in 31.8955 Ordinary 
                                    Share ADRs purchased at a price
                                    of $45.8689 per ADR.

The Directors and the Company were advised of this information on 12 January
2004.

S M Bicknell

Company Secretary

12 January 2004




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