Director Shareholding

GlaxoSmithKline PLC
13 January 2004

                              Director's Interests

I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-

Mr J D Coombe                       The Administrators of the GlaxoSmithKline 
                                    Annual Investment Plan notified the Company 
                                    and Mr Coombe on 13 January 2004 that he had
                                    increased his interest by 109 Ordinary 
                                    Shares at a price of £12.17 per share
                                    following the re-investment of the dividend 
                                    paid to shareholders on 6 January 2004.


S M Bicknell
Company Secretary
13 January 2004




                      This information is provided by RNS
            The company news service from the London Stock Exchange