Director Shareholding

GlaxoSmithKline PLC
08 March 2004



                              Director's Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.
                    
8 March 2004        The Administrators of the SmithKline Beecham Employee 
                    Benefit Trust ("the Trust") notified the Company on 8 March 
                    Directors Dealing2004 that 1,563 Ordinary shares had been 
                    transferred from the Trust to participants in the 
                    GlaxoSmithKline Annual Investment Plan.

The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, John Coombe is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.


S M Bicknell

Company Secretary

8 March 2004



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