Director Shareholding

GlaxoSmithKline PLC
04 June 2004


Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


               The Administrators of the GlaxoSmithKline US Retirement Savings 
               Plan ("the Plan") notified GlaxoSmithKline plc on 4 June 2004, 
               that as a result of movement in the fund on 3 June 2004, the 
               number of Ordinary Share ADRs held by the fund had increased from 
               18,908,635 to 18,920,670 at an average price of $42.08.

The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Dr T Yamada are therefore potentially
interested in the shares held in the fund from time to time in the same way as
other employees or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell
Company Secretary

4 June 2004

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