Director Shareholding

GlaxoSmithKline PLC
06 July 2004


                              Director's Interests


I give below details of changes in interests in the Ordinary Shares and American
Despositary Receipts (ADRs) of GlaxoSmithKline plc in respect of the
under-mentioned directors:-

Dr J P Garnier      The Administrators of the GlaxoSmithKline Performance Share 
                    Plan notified the Company and Dr Garnier on 6 July 2004 that 
                    his interest had notionally increased by 1,698.713 ADRs at a 
                    price of $42.05 per ADR following the notional re-investment 
                    of the dividend paid to shareholders on 1 July 2004.

Dr T Yamada         The Administrators of the GlaxoSmithKline Performance Share 
                    Plan notified the Company and Dr Yamada on 6 July 2004 that 
                    his interest had notionally increased by 509.614 ADRs at a 
                    price of $42.05 per ADR following the notional re-investment 
                    of the dividend paid to shareholders on 1 July 2004.

Mr J D Coombe       The Administrators of the GlaxoSmithKline Performance Share 
                    Plan notified the Company and Mr Coombe on 6 July 2004 that 
                    his interest had notionally increased by 1,040.917 Ordinary 
                    Shares at a price of £11.67 per Ordinary Share following the 
                    notional re-investment of the dividend paid to shareholders 
                    on 1 July 2004.

The notional dividends accrued will be paid out in proportion to the percentage
of participants' Performance Share Plan holdings that vest following the end of
the relevant three year measurement period.


S M Bicknell
Company Secretary

6 July 2004


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