Director Shareholding

GlaxoSmithKline PLC
24 May 2004




Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
Plan") notified GlaxoSmithKline plc on 21 May 2004, that as a result of movement
in the fund on 20 May 2004, the number of Ordinary Share ADRs held by the fund
had decreased from 18,866,129 to 18,837,088 at an average price of $42.18.



The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Dr T Yamada are therefore potentially
interested in the shares held in the fund from time to time in the same way as
other employees or former employees of GlaxoSmithKline plc and its subsidiaries.





S M Bicknell

Company Secretary



24 May 2004


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