Director Shareholding

GlaxoSmithKline PLC
05 October 2004




                              Director's Interests

I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc in respect of the under-mentioned director:-



Dr J P Garnier   The Administrators of the GlaxoSmithKline Performance Share 
                 Plan notified the Company and Dr Garnier on 4 October 2004 that 
                 he had increased his interest by 295.235 Ordinary Share ADRs at 
                 a price of $43.650 per Ordinary Share ADR following the 
                 re-investment of the dividend paid to shareholders on 30 
                 September 2004.






S M Bicknell
Company Secretary



5 October 2004






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