Director Shareholding

GlaxoSmithKline PLC
15 November 2004



                              Director's Interests

I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-


Mr J D Coombe       The Administrators of the GlaxoSmithKline Annual Investment 
                    Plan notified the Company and Mr Coombe on 7 October 2004 
                    that he had increased his interest by 126 Ordinary Shares at 
                    a price of £12.00 per share following the re-investment of 
                    the dividend paid to shareholders on 30 September 2004.

                    The Administrators have today informed the Company that the 
                    share price at which Mr Coombe's dividend was reinvested was 
                    £12.07 rather than £12.00 and that his interest therefore 
                    increased by 125 shares rather than 126 as previously 
                    announced.



S M Bicknell
Company Secretary

15th November 2004


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