Director Shareholding

GlaxoSmithKline PLC 11 April 2005 Director's Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 06 April 2005 The Administrators of the SmithKline Beecham Employee Benefit Trust ("The Trust") notified the Company on 11 April 2005 that 649 Ordinary shares in the Company had been sold on behalf of a participant in the GlaxoSmithKline Bonus Investment Plan at a price of £12.28 per share. The Trust is a discretionary fund of which all non US employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Julian Heslop is therefore interested in the shares held in the fund from time to time in the same way as other non US employees or former employees of GlaxoSmithKline plc and its subsidiaries. S M Bicknell Company Secretary 11 April 2005 This information is provided by RNS The company news service from the London Stock Exchange

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