Director Shareholding

GlaxoSmithKline PLC
01 April 2005

                              Directors' Interests


I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.

On 31 March 2005, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share allocation arrangements for non-executive Directors for the
period of service from 1 January to 31 March 2005, as listed below.

Non Executive Director         Ordinary Shares        American Depository Shares
                                                                 (ADS)
Sir Christopher Gent              2,054.23
Mr Lawrence Culp                                               595.04
Sir Crispin Davis                 1,643.39
Sir Deryck Maughan                                             595.04
Sir Ian Prosser                   1,129.83
Dr Ronaldo Schmitz                 903.86
Dr Lucy Shapiro                                                148.76
Sir Robert Wilson                  513.56


The Company and the directors were informed of these allocations on 1 April
2005.

S M Bicknell
Company Secretary
1 April 2005


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