Director Shareholding

GlaxoSmithKline PLC
10 June 2005

                              Director's Interests


I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £13.605 per Ordinary Share on 09 June
2005 through the Company's ShareReward Plan ("the Plan") which Mr Heslop entered
on 5 October 2001:




Mr J S Heslop           Acquisition of 10 Ordinary Shares under the partnership 
                        element of the Plan (personal contribution)

                        Acquisition of 10 Ordinary Shares under the matching 
                        element of the Plan (Company contribution)


Mr Heslop and the Company were advised of this information on 10 June 2005.


S M Bicknell
Company Secretary

10 June 2005


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