Directorate Change

GlaxoSmithKline PLC
28 September 2007


                         GLAXOSMITHKLINE PLC ANNOUNCES
                        CHANGE TO THE BOARD OF DIRECTORS 


GlaxoSmithKline plc (GSK) announces that Professor Sir Roy Anderson has been
appointed a Non-Executive Director and will join the Board of the Company with
effect from 1st October 2007.

Professor Anderson is Professor of Infectious Disease Epidemiology, Imperial
College, London and, until 30 September 2007, Chief Scientific Advisor to the
UK's Ministry of Defence.

In commenting on his appointment, Sir Christopher Gent, Chairman of GSK, said:

"I am delighted that Professor Anderson has agreed to join the Board. In
addition to fulfilling the usual responsibilities of a Non-Executive Director,
he will spend time within our research and development organisation and, with
his experience, will provide the Board with valuable insights to scientific
developments outside GSK."

Professor Anderson's biographical details are given below together with a table
showing the membership of the Board with effect from 1st October 2007.

Simon Bicknell
Company Secretary

28th September 2007


NOTES 

The Board has determined that Professor Anderson is independent in accordance
with the Combined Code on Corporate Governance.

BIOGRAPHICAL DETAILS 

Professor Sir Roy Anderson

Age 60. Professor Anderson is the Professor of Infectious Disease Epidemiology
in the Faculty of Medicine, Imperial College, London and, until 30 September
2007, the Chief Scientific Adviser at the Ministry of Defence in the United
Kingdom. It was announced on 21 June 2007 that Professor Anderson will succeed
Sir Richard Sykes as Rector of Imperial College in the summer of 2008.

He is a Fellow of the Royal Society, a Fellow of the Academy of Medical
Sciences, a Fellow of the Royal Statistical Society, Honorary Fellow of the
Institute of Actuaries and a Foreign Associate Member of the Institute of
Medicine at the US National Academy of Sciences.

He has published over 450 scientific papers on the epidemiology, population
biology, evolution and control of a wide variety of infectious disease agents,
including HIV, BSE, vCJD, parasitic helminths and protozoa, and respiratory
tract viral and bacterial infections.

His principal research interests are epidemiology, biomathematics, demography,
parasitology, immunology and health economics. He also has a keen interest in
science policy and the public understanding of science.

He received a Knighthood in the Queen's Birthday Honours in June 2006.


                                BOARD MEMBERSHIP
                       WITH EFFECT FROM 1ST OCTOBER 2007


Sir Christopher Gent       Chairman
Sir Ian Prosser            Senior Independent Non-Executive Director

Dr J-P Garnier             Chief Executive Officer
Mr J S Heslop              Chief Financial Officer
Dr Moncef Slaoui           Executive Director, Chairman, Research & Development

Professor Sir Roy Anderson    Independent Non-Executive Director
Dr Stephanie Burns            Independent Non-Executive Director
Mr H Lawrence Culp            Independent Non-Executive Director
Sir Crispin Davis             Independent Non-Executive Director
Sir Deryck Maughan            Independent Non-Executive Director
Dr Daniel Podolsky            Independent Non-Executive Director
Dr Ronaldo Schmitz            Independent Non-Executive Director
Mr Tom De Swaan               Independent Non Executive Director
Sir Robert Wilson             Independent Non-Executive Director

Enquiries:


UK Media enquiries:                    Philip Thomson            [phone]
                                       Alice Hunt                [phone]
                                       Joss Mathieson            [phone]
                                       Claire Brough             [phone]

US Media enquiries:                    Nancy Pekarek             [phone]
                                       Mary Anne Rhyne           [phone]

European Analyst/Investor enquiries:   David Mawdsley            [phone]
                                       Sally Ferguson            [phone]

US Analyst/ Investor enquiries:        Frank Murdolo             [phone]
                                       Tom Curry                 [phone]


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