Holding(s) in Company

GlaxoSmithKline PLC
21 February 2003



GLAXOSMITHKLINE plc - Notification of Major Interests in Shares


GlaxoSmithKline plc (the Company) yesterday received notification from Barclays
in compliance with Part VI of the Companies Act 1985 (as amended), that on 17
February 2003 it had the following interests in the Company's Ordinary Shares of
25 pence:

Registered Holder                                          Current shareholding

Barclays Capital Securities Limited                                   1,288,771
Barclays Private Bank and Trust Limited                                 732,755
Barclays Nikko Global Investors Limited                               2,102,818
Barclays Private Bank Limited                                         3,082,350
Woolwich Pension Fund Trust Company Limited                             337,150
Barclays Global Fund Advisors                                         1,806,595
Barclays Life Assurance Company Limited                              10,505,429
Barclays Global Investors Japan Trust & Banking Co Limited            6,205,095
Barclays Global Investors Australia Limited                           1,876,447
Barclays Global Investors, N.A.                                      62,414,400
Woolwich Life Limited                                                   995,000
Barclays Global Investors Japan                                         112,020
Barclays Global Investors Limited                                    88,449,756
Barclays Bank Trust Company Limited                                   1,071,469
TOTAL                                                               180,980,055


This total holding represents 3.00 per cent of the issued share capital of the
Company.


S M Bicknell

Company Secretary

21 February 2003

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