Re Agreement

GlaxoSmithKline PLC 29 October 2001 Issued: London and Toronto, October 29th, 2001 GlaxoSmithKline and Biovail Sign Licensing Agreements For Once Daily Formulation of Wellbutrin and Distribution Rights for Zovirax Ointment & Cream GlaxoSmithKline plc (GSK) and Biovail Corporation (NYSE, TSE:BVF) today announce that Biovail has licensed to GSK a novel controlled-release, once-daily formulation of bupropion hydrochloride (HCI) for sales and distribution on a world-wide basis, excluding Canada. Bupropion HCI, which is marketed for the treatment of depression as Wellbutrin SR by GSK, is currently sold in a sustained-release, twice daily, dosage format. Under the terms of the Wellbutrin Once Daily agreement, Biovail will manufacture and supply the product to GSK for a share of the future sales of the product. GSK and Biovail will co-promote Wellbutrin SR and, Biovail will have the option to co-promote Wellbutrin Once Daily upon approval, in the United States. GSK and Biovail intend to file a New Drug Application (NDA) for Wellbutrin Once Daily with the United States Food and Drug Administration (FDA) during the first half 2002. In addition, Biovail has acquired exclusive promotion and distribution rights for Zovirax Ointment for the United States and Puerto Rico. Under the terms of the agreement, GSK will manufacture and supply Zovirax Ointment and Zovirax Cream to Biovail and, in return, Biovail will pay GSK $133 million for certain rights to the products, subject to certain conditions. Biovail will begin promotional efforts related to Zovirax Ointment in January 2002 and intends to launch Zovirax Cream upon FDA approval. In order to gain FDA approval for Zovirax Cream, GSK will work with the FDA to reinstate a New Drug Application (NDA) previously filed by the company for the product. GSK will also conduct a paediatric Phase IV study for Zovirax Cream. Commenting on the agreements, Dr Jean-Pierre Garnier, Chief Executive Officer, GlaxoSmithKline said: 'This agreement with Biovail represents a further strengthening of our late stage product development pipeline and is indicative of our intention to become the partner of choice for those companies wishing to maximise the commercial potential of their products and increase their global presence. The new Wellbutrin Once Daily will offer physicians greater prescribing flexibility, the potential for improved patient convenience and compliance as well as a modified drug release profile.' Eugene Melnyk, Chairman of the Board, Biovail Corporation commented: 'Our agreements with GlaxoSmithKline are the latest example of Biovail's stated mission of continuing to grow and expand our base business and to capitalise on the opportunities that our rich and deep pipeline of controlled-release and FlashDoseO products represent. Our new association with GlaxoSmithKline for the licensing and promotion of Wellbutrin Once Daily and Wellbutrin SR and, the acquisition of US distribution rights for Zovirax topical products, further demonstrates our commitment to building Biovail into one of North America's premier developers and marketers of pharmaceutical products.' The transaction will be notified under the Hart Scott Rodino pre-merger notification program, and will become effective only upon approval of the transaction by the US Federal Trade Commission. GlaxoSmithKline - one of the world's leading research-based pharmaceutical and healthcare companies - is committed to improving the quality of human life by enabling people to do more, feel better and live longer. Biovail Corporation is an international full-service pharmaceutical company, engaged in the formulation, clinical testing, registration, manufacture, sale and promotion of pharmaceutical products utilising advanced drug delivery technologies. --Ends-- Enquiries: UK Media enquiries Martin Sutton (020) 8966 8372 Philip Thomson (020) 8966 8372 Alan Chandler (020) 8966 8372 US Media enquiries Nancy Pekarek (215) 751 7709 Mary Anne Rhyne (919) 483 2839 European Analyst/Investor enquiries Jennie Younger (020) 8966 8378 Duncan Learmouth (020) 8966 5961 Anita Kidgell (020) 8966 8369 US Analyst/Investor enquiries Frank Murdolo (215) 751 7002 Tom Curry (215) 751 5419 Cautionary statement regarding forward-looking statements Under the safe harbor provisions of the US Private Securities Litigation Reform Act of 1995, the Company cautions investors that any forward-looking statements or projections made by the Company, including those made in this Announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Factors that may affect the Group's operations are described under Risk Factors in the Operating and Financial Review and Prospects in the Company's Annual Report on Form 20-F for 2000, filed with the US Securities and Exchange Commission.

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