Transaction in Own Shares

GlaxoSmithKline PLC
22 September 2004

                              GlaxoSmithKline PLC



GlaxoSmithKline plc (the "Company") announces that in accordance with the
authority granted by shareholders at the Company's Annual General Meeting on 17
May 2004 it purchased 500,000 of it's Ordinary shares of 25 pence each ("shares
") on 22 September 2004 at a price of 1192.5 pence per share.

The Company intends to hold these shares in Treasury.

Following the purchase of these shares, the Company holds 45,923,000 of it's
shares in Treasury and has 5,889,078,094 shares in issue (excluding Treasury
shares).

This announcement does not constitute, or form part of, an offer or any
solicitation of an offer to purchase or subscribe for securities in any
jurisdiction.


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