Transaction in Own Shares

GlaxoSmithKline PLC 26 September 2006 GlaxoSmithKline plc (the "Company") announces that in accordance with the authority granted by shareholders at the Company's Annual General Meeting on 17 May 2006 it purchased 350,000 of its Ordinary shares of 25 pence each ("shares") on 26 September, 2006 at a price of 1428.4394 pence per share. The Company intends to hold these shares in Treasury. Following the purchase of these shares, the Company holds 197,091,678 of its shares in Treasury and has 5,789,141,868 shares in issue (excluding Treasury shares). This announcement does not constitute, or form part of, an offer or any solicitation of an offer to purchase or subscribe for securities in any jurisdiction. This information is provided by RNS The company news service from the London Stock Exchange

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