Transaction in Own Shares

GlaxoSmithKline PLC
29 November 2004



                              GlaxoSmithKline PLC

GlaxoSmithKline plc (the "Company") announces that in accordance with the
authority granted by shareholders at the Company's Annual General Meeting on 17
May 2004 it purchased 885,000 of it's Ordinary shares of 25 pence each ("shares
") on 29 November 2004 at a price of 1127.7 pence per share.

The Company intends to hold these shares in Treasury.


Following the purchase of these shares, the Company holds 54,928,000 of it's
shares in Treasury and has 5,878,985,023 shares in issue (excluding Treasury
shares).


This announcement does not constitute, or form part of, an offer or any
solicitation of an offer to purchase or subscribe for securities in any
jurisdiction.




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